Proteogenomic Study of the Effect of an Improved Mixed Diet of Live Preys on the Aquaculture of Octopus vulgaris Paralarvae

The common octopus is the most demanded cephalopod species for human consumption. Despite important advances realized recently, main bottleneck commercial production of octopus, Octopus vulgaris , mass mortality paralarvae in first 15–20 days post-hatching (dph), with responsible factors still unknown. Thus, identification limiting culture is, therefore, crucial their aquaculture. This study investigates proteomic and transcriptomic responses fed on an improved live preys-mixed diet (M) compared to Artemia -based (A) reference diet. M resulted highest specific growth rate obtained date under conditions. supported by proteins genes over-expressed group being linked cell cycle replication, structural components, development nervous system. Furthermore, differential nutritional regulation several seems indicate that, instead fatty acids, preferred fuels cephalopods would be carbohydrates. Also, provides a better nutrient balance, which has allowed carrying out this comparative optimal conditions at more advanced stage (20 dph) than previous studies. Moreover, extended up 40 dph showed time proper pre-settlement behavior.